Are you a PhD holder interested in Postdoctoral Fellowships? Jackson Laboratory, California is offering Postdoctoral Fellowships in various research fields. Apply today to pursue your research interests in a stimulating academic environment!
1. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Tewhey Lab at The Jackson Laboratory in Bar Harbor, Maine is seeking a Postdoctoral Associate to join our team of scientists working to understand the precise genetic mechanisms underlying human complex traits and the impact genetic variation has on gene regulatory function. Our group develops and applies novel high-throughput genetic techniques (e.g. MPRA and CRISPR based screens) to comprehensively characterize non-coding regions of the genome and leverages these datasets to construct computational models to predict the activity of cis-regulatory elements across cell types and states.
Application Deadline: Open Until Filled
2. Postdoctoral Position
Summary of Postdoctoral Fellowship:
This position will be focused on a new collaborative project to characterize donor-derived organoid models and assess their utility in precision medicine approaches to treating Alzheimer’s disease. This process encompasses a range of computational and systems biology approaches, including big data analysis through dimensional reduction, inference of disease relevance by comparison to matched human data, and pharmacogenomic analysis of targeted therapies. This project is embedded in a broader set of studies using mouse and non-human primate models to enable unique cross-species analysis to accelerate the discovery of treatments for dementia.
Application Deadline: Open Until Filled
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3. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Of relevance to this position, Drs. Sasner and Howell are two of the leads on MODEL-AD (Model Organism Development and Evaluation of Late-onset AD), an NIA-funded consortium charged with developing improved mouse models of AD for preclinical testing. Drs. Sasner and Howell lead the Disease Modeling Project, which is responsible for creating novel mouse models expressing AD-relevant genetic risk factors and using translationally-relevant assays (e.g. fluid biomarkers, neuropathology, and multi-omics) to characterize disease progression.
Application Deadline: Open Until Filled
4. Postdoctoral Position
Summary of Postdoctoral Fellowship:
The Tarchini Lab at The Jackson Laboratory is seeking a Postdoctoral Associate to complete a team currently composed of two postdocs, one research assistant and rotating students or shorter term trainees. The laboratory focuses on cell polarity mechanisms and their impact on the morphogenesis of sensory “hair” cells in the mouse auditory and vestibular organs, including hearing and balance ability. We are particularly interested in discovering new protein complexes organizing and elongating the stereocilia bundle, the apical hair cell compartment capturing sound or head movements.
Application Deadline: Open Until Filled
5. Postdoctoral Position
Summary of Postdoctoral Fellowship:
Our research goals are to: i) define the molecular pathways that regulate splicing factors in normal and cancer cells, as well as during cell differentiation; ii) uncover causal splicing alterations in breast tumors; and iii) identify splicing factors and spliced isoforms which could be used as biomarkers to predict disease progression or drug-response, or as targets for RNA-based therapeutics. Our research uses 3D cell culture models, mouse models including patient-derived xenograft, as well as large clinical datasets, and leverages cutting-edge approaches such as RNA-targeting CRISPR, short- and long-read RNA-sequencing, and single-cell approaches, to decipher the role of spliced isoforms and their regulators.
Application Deadline: Open Until Filled
