Are you a Master’s graduate looking for fully funded PhD opportunities? Explore the range of funded PhD programs available at the University of Cambridge, England. Apply online now and kickstart your doctoral journey!
1. Fully Funded PhD Position in Unlocking the code within the code: Using AI to decipher the role of codon usage in protein synthesis and gene regulation
Summary of PhD Program:
The genetic code contains 61 codons encoding 20 amino acids and most amino acids are therefore encoded by two or more ‘synonymous’ codons. Despite producing the same protein, the choice of one synonymous codon over another plays an important role in gene regulation [1,2]. Some codons slow down translation, which in turn triggers mRNA degradation and halt protein synthesis. Protein synthesis is often dysregulated in cancer, making mRNA translation an attractive therapeutic target.
Application Deadline: 31 October 2024
2. Fully Funded PhD Position in Multi-modal spatial data integration to predict breast cancer treatment response
Summary of PhD Program:
Breast cancer patients show highly variable responses to different treatments. Some respond durably, while others start by responding but eventually relapse and a subset show little evidence of response at all. The biological basis of these differences remains obscure but the spatial architecture of tumours is likely a major contributor. Novel technologies for multiplexed molecular measurements of tumour tissues that preserve spatial relationships offer the opportunity to precisely dissect the contribution of the spatially resolved multicellular tumour ecosystem as a response driver.
Application Deadline: 31 October 2024
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3. Fully Funded PhD Position in Modelling new therapeutic approaches for neoadjuvant treatment of high grade serous ovarian carcinoma
Summary of PhD Program:
The aim of the project is to develop new therapeutic approaches for neoadjuvant therapy of BRCA1 mutated HGSC. These patients have adverse outcomes despite initial response to platinum-based chemotherapy and PARP maintenance treatment. The project will focus on modifiers of chemotherapy induced senescence and combination therapy with new drugs targeting DNA damage response. The experimental approach will combine cell fate analysis using in vitro and in vivo lineage tracing using existing PDX and CRISPR engineered models that can evaluate coincident immunological responses. Pharmacodynamic effects on the DNA damage response pathways will be measured using single cell technologies, including CyTOF and imaging mass cytometry of pre-clinical models and patient samples.
Application Deadline: 31 October 2024
4. Fully Funded PhD Position in Mapping cellular trajectories in the senescence spectrum
Summary of PhD Program:
Senescence can be triggered by various stimuli across diverse cellular contexts. We are particularly interested in oncogene-induced senescence (OIS), which occurs in the physiological diploid state as an early event in tumour initiation. OIS functions autonomously as a tumour suppressor mechanism, though it is conceptually distinct from tumour-initiating cells (TIC). Our recent study suggests that senescence is not a singular entity but rather a continuum of dynamic cellular functionality and plasticity, forming what we term the ‘senescence spectrum.’
Application Deadline: 31 October 2024
5. Fully Funded PhD Position in Investigating the low-to-high grade glioma transition using spatial multi-omics
Summary of PhD Program:
This project will be hosted in the Spatial Profiling and Annotation Centre of Excellence (SPACE), an interdisciplinary laboratory dedicated to developing and applying spatial molecular profiling technologies established by the group of Prof. Hannon after a successful Cancer Grand Challenge project. The laboratory routinely uses a variety of spatial omics technologies including spatial transcriptomics, multiplexed immunohistochemistry, single-cell genomics, 3D whole-organ microscopy and more, and actively develops new technologies for spatial epigenomics and multi-omics.
Application Deadline: 4 November 2024
6. Fully Funded PhD Position in Immune Hedgehog signalling dynamics in health and disease
Summary of PhD Program:
While we and others have discovered pivotal roles of the Hedgehog pathway in immune cells, Hedgehog signalling dynamics and interaction partners within the cells of the immune system remain elusive. The project aims to shed light on this by using chromobody technology, bespoke mouse models and proximity labelling techniques. The student will work with murine and human immune cells and the fundamental mechanistic insight gained may inform novel therapeutic entry points into cancer, infection and autoimmunity.
Application Deadline: 31 October 2024
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7. Fully Funded PhD Position in Developing digital tools to support a personalised preventative pathway for children’s mental health
Summary of PhD Program:
The Department of Psychiatry, University of Cambridge, is pleased to announce a Studentship to conduct research for a doctoral degree to start in January 2025 for a duration of three years. The PhD student will be a part of the UKRI Future Leaders Fellowship project (PI: Moore) – Transforming child mental health: co-designing, building and evaluating digitally enabled, personalised, prevention pathways. Professor John Suckling will co-supervise. The Studentship is suitable for candidates with a good degree in engineering, computer science, genetics, mathematics, psychology, biology, medicine, neuroscience, mathematics, biochemistry, or a related discipline.
Application Deadline: 31 October 2024
8. Fully Funded PhD Position in Delineating piRNA-guided silencing of transposable elements
Summary of PhD Program:
This project aims to uncover the molecular mechanisms that underlie the piRNA pathway mainly using the fruit fly Drosophila melanogaster as a model. While a rough framework of the piRNA machinery has been established in recent years, the precise hierarchy of the events that result in faithful transposon silencing is not yet fully understood. In your project you will exploit tissue culture as well as in vivo models, and carry out various biochemical, proteomic, imaging, genomics (including state-of-the-art RNA and chromatin profiling methods), and computational approaches to study piRNA-guided transposon control.
Application Deadline: 31 October 2024
9. Fully Funded PhD Position in Data-driven mechanics
Summary of PhD Program:
Mechanical properties of materials are usually measured by simple one-dimensional tests. The growing field of data-driven mechanics requires development of experimental methods to obtain large quantities of multi-axial data from a single test. To complement this data is the requirement to develop computational methods that can deal with the inevitable measurement noise. We are starting a new project with the aim to use: (i) lab-based flux enhanced tomography for full field measurement of deformation fields and X-ray diffraction measurements of elastic strains, and (ii) associated data-driven material model discovery techniques.
Application Deadline: 15 November 2024
10. Fully Funded PhD Position
Summary of PhD Program:
The Universities of Cambridge and East Anglia, together with the Wellcome Sanger Institute, invite applications for up to 7 fellowships in the PhD Programme for Health Professionals, to be taken up by the end of 2025. The fellowships provide funding for clinical salary, University Composition Fees and research consumables for 3 years. Prior to commencement, the Programme can provide up to three months of additional salary support, enabling successful applicants to experience research in different groups, before making an informed choice of project and supervisor.
Application Deadline: 5 November 2024
11. Fully Funded PhD Position in Future Infrastructure and Built Environment: Unlocking Net Zero
Summary of PhD Program:
We have funding for a number of 1+3 MRes/PHD studentships, in collaboration with industry, as part of our EPSRC Centre for Doctoral Training in Future Infrastructure and Built Environment: Unlocking Net Zero (FIBE3 CDT), under the four following themes:
-Current and disruptive technologies
-Circularity and whole life approach
-Al-driven digitalisation and data
-Risk-based systems thinking and connectivity
Application Deadline: 16 May 2025
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12. Fully Funded PhD Position in Health Data Science
Summary of PhD Program:
The project will harness large-scale human genetic resources with deep phenotyping data (e.g., UK Biobank, INTERVAL, BELIEVE) to interrogate the molecular aetiology of BMI and identify discrete axes of risk that may inform more personalized medicine and identify therapeutic targets. The student will employ genomic and computational approaches (e.g. GWAS, polygenic scores, Mendelian randomization, machine learning methods) integrating genetic data, health records, and multi-omics data from blood.
Application Deadline: 31 October 2024
13. Fully Funded PhD Position in The fabric of London: two centuries of fire insurance policies
Summary of PhD Program:
Aviva and CamPop have digitised fire insurance records from the late seventeenth to the mid-nineteenth century: https://amicablecontributors.com/. Most of these policies relate to buildings in London not only the capital but also the largest city in Europe and a city dramatically growing and changing over this period. The CDA holder will have scope to develop their own project with these sources. One option would be to focus on building history and the materials of construction. Another would be to concentrate on economic history and the ownership patterns revealed by the policies, with a prosopographical study of property owners.
Application Deadline: 3 December 2024
14. Fully Funded PhD Position in Structured inter-religious encounter and anti-discrimination education: a study
Summary of PhD Program:
This practice-based PhD project will critically investigate approaches to structured interreligious encounter and exchange as deployed in the work of The Faith & Belief Forum, whose programmes span schools, universities, communities and workplaces. Augmenting previous studies of interfaith work, the project will include a unique focus on the interaction between such programmes and the goal of reducing prejudice and discrimination, whether in terms of religion or belief, gender, race, nationality or other intersectional identities.
Application Deadline: 3 December 2024
15. Fully Funded PhD Position in common ground: exploring methods of communication at a system and landscape level for floods and other risks in the UK
Summary of PhD Program:
This Collaborative Doctoral Award would give you the opportunity to shape the UK’s climate adaptation programme. Partnering with Arup and the EA in their recently launched FENS2100+ project, you will gain privileged insights from practitioners and the local communities at risk and pilot their research-led designs during their PhD. The aim of this project is to explore and propose methods of communication at a system and landscape level for floods and other risks in the UK.
Application Deadline: 7 January 2025
16. Fully Funded PhD Position in A phonetic investigation of speaker attribution and its implications for legal contexts
Summary of PhD Program:
In transcribing an evidential recording of an interaction involving two or more speakers, speaker attribution is the process of assigning each utterance in the transcript to a speaker. The police may believe that particular individuals were involved in the interaction, but recording quality is often poor, so exactly how many people were present and their identities can be unclear. Transcription of recordings is typically conducted in-house by police officers or other staff with no linguistic or phonetic training.
Application Deadline: 3 December 2024
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17. Fully Funded PhD Position in The Portraiture of Rowland Lockey (c.1566-1616): A Historical and Technical Examination
Summary of PhD Program:
The studentship will provide an opportunity to undertake technical art-historical research on paintings attributed to Lockey in the collection of the National Trust, understanding the use of techniques such as MA-XRF, cross-section sampling, and X-radiography. Assisted by Trust curators the award holder will research documentary evidence in the Hardwick archives of Lockey’s work for patrons such as Elizabeth, Countess of Shrewsbury, and her son, William Cavendish.
Application Deadline: 7 January 2025