12 Postdoctoral Fellowships at University of Pennsylvania, Pennsylvania, United States

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Are you a PhD holder interested in Postdoctoral Fellowships? University of Pennsylvania, Pennsylvania, United States is offering Postdoctoral Fellowships in various research fields. Apply today to pursue your research interests in a stimulating academic environment!

1. Postdoctoral Position

Summary of Postdoctoral Fellowship:

The goal is to develop a mechanistic understanding of the pediatric disease biliary atresia. Although there are several possible approaches to the project, it will involve studying potential toxic causes and effects of fetal extrahepatic bile duct injury using a combination of animal models, microscopy, and transcriptomics approaches; the role of redox stress is a particular interest. See the following for examples of previous and ongoing work on this project from the lab: PMIDs 25947162 and 31562906 set the foundation, and more recently: 38578745 and 37611641. A new model of the disease we have proposed is in press.

Application Deadline: Open Until Filled

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2. Postdoctoral Position

Summary of Postdoctoral Fellowship:

The Department of Ophthalmology is seeking a full-time postdoctoral scientist to work under the direction of the Principal Investigator, and perform duties associated with projects aiming to use gene therapy to tackle inherited retinal disorders (IRDs). Research approaches include therapeutic prime editing and induced pluripotent stem cell (iPSC) retinal organoid disease modeling. Further, the position requires assisting the principal investigator with grant and manuscript writing.

Application Deadline: Open Until Filled

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3. Postdoctoral Position

Summary of Postdoctoral Fellowship:

The Miner laboratory studies the role of cytosolic nucleic acid sensors in rare diseases, antiviral immunity, autoimmunity, neurodegeneration, and DNA damage responses. In our laboratory, rare disease research is a starting point to define fundamental biological mechanisms. We also prioritize development of novel therapies for patients with rare monogenic diseases. We have 2 new R01s as well as private funding to support multiple postdocs. We have discovered several new mechanisms of autoimmunity, antiviral immunity, neurodegeneration, and autoinflammation.

Application Deadline: Open Until Filled

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4. Postdoctoral Position

Summary of Postdoctoral Fellowship:

The project will involve coronavirus pathogenesis. We work with coronavirus host interactions with focus on antagonism of the innate immune response and unfolded protein responses with projects in SARS-CoV-2, MERS-CoV, the common cold CoVs 229E, NL63 and OC4 3and the model murine coronavirus (MHV). Projects will involve tissue culture infections in BSL3 lab including primary nasal epithelial cells and mouse models.

Application Deadline: Open Until Filled

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5. Postdoctoral Position

Summary of Postdoctoral Fellowship:

The Artificial Intelligence for Ambulatory Care Innovation (AI-4-AI) Lab seeks a highly motivated and talented Postdoctoral Researcher to join our team in revolutionizing ambulatory care using multimodal video/audio learning techniques. As a member of our multidisciplinary research team, you will be responsible for developing and working with students on innovative solutions that enhance patient-clinician communication quality, efficiency, and effectiveness. This position offers an excellent opportunity to contribute to cutting-edge research and shape the future of healthcare technology.

Application Deadline: Open Until Filled

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6. Postdoctoral Position

Summary of Postdoctoral Fellowship:

The functions of this position will include: development of targeted lipid nanoparticle (LNP) formulations specifically for in vivo use, and performing all required quality controls, and most critically, developing new techniques to both large scale produce mRNA and targeted LNP. They will be required to develop their own assays and methods, troubleshoot these methods, and analyze the data to determine the next steps in development.

Application Deadline: Open Until Filled

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7. Postdoctoral Position

Summary of Postdoctoral Fellowship:

We are seeking a creative and self-motivated postdoctoral researcher interested in studying the factors that contribute to inter-individual variability in the analgesic response to NSAIDs. The project seeks to identify the factors that contribute to the need for supplemental opioid after third molar (wisdom tooth) extraction and identify biomarkers that are predictive of analgesic response to NSAIDs. The ultimate goal of this work is to enable development and testing of a treatment algorithm that can be incorporated into clinical care to facilitate a precision medicine approach to pain management. The postdoctoral researcher will work closely with the PI (Dr. Theken) and other members of the study team.

Application Deadline: Open Until Filled

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8. Postdoctoral Position

Summary of Postdoctoral Fellowship:

A POSTDOCTORAL POSITION to continue and expand studies into the mechanisms of immuno-suppression in the primary tumor and metastatic microenvironment and importance of these mechanisms in cancer therapies (as described in Cancer Cell 2017 and 2019, Cell Metab 2022, Nat Cancer 2020 and 2022 and J Clin Invest 2021).

Application Deadline: Open Until Filled

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9. Postdoctoral Position

Summary of Postdoctoral Fellowship:

We seek a talented individual with strong drive, excellent communication skills, and a positive attitude to join our team and perform world-class science in beautiful Philadelphia! We have a newly funded study focused on unraveling the mechanisms underlying type I diabetes (T1D) and identifying novel biomarkers of autoimmunity. As a postdoctoral researcher, you will have the unique opportunity to work with primary human tissues and collaborate with leading experts in the field.

Application Deadline: Open Until Filled

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10. Postdoctoral Position

Summary of Postdoctoral Fellowship:

Seeking a talented and highly motivated postdoctoral fellow to join the Center for Health Behavior Research (CHBR) based in the University of Pennsylvania Perelman School of Medicine. The Center, directed by Dr. Karen Glanz, focuses on advancing the development, application, and testing of health behavior measurement and theories. We conduct and collaborate on innovative research on prevention, intervention, and program development for health behavior change. CHBR is also home to the CDC-funded UPenn Prevention Research Center, part of a unique university research center and a national network of 20 centers. The ideal candidate should be interested in the Center for Health Behavior Research’s work in the development, application, and testing of health behavior interventions, measurement and theories. The postdoctoral fellow will have opportunities to collaborate on interdisciplinary research, secondary data analyses, and to work on new studies. The position is for two years (one year with renewal based on successful performance). Start date is negotiable.

Application Deadline: Open Until Filled

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11. Postdoctoral Position

Summary of Postdoctoral Fellowship:

A Postdoctoral Researcher position is available for a highly motivated applicant in the laboratory of Dr. Fiona Simpkins at the University of Pennsylvania. Our focuses are to understand resistance mechanisms to targeted therapies such as DNA Damage Repair inhibitors (DDRi), to sequence DDRi with Immuno-Oncology (IO) drugs, and to identify biomarkers or response to these agents. We have developed a preclinical drug development program in the Ovarian Cancer Research Center with the goal of moving novel laboratory therapeutic discoveries into the clinic. We have developed >150 patient derived xenografts (PDX) models, patient-derived organoids, and primary tumor cultures from ovarian and endometrial cancers. These PDX models mimic the original tumors, thereby accelerating the translation of preclinical study results into clinical trials for patients. Also, we are “humanizing” our models by autologous tumor infiltrating lymphocyte (TIL) and macrophage (TAM) transfer, creating an autologous in vivo model system. 

Application Deadline: Open Until Filled

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12. Postdoctoral Position

Summary of Postdoctoral Fellowship:

The Diab laboratory is seeking applicants for a postdoctoral fellow position to be supported by our institutional Tumor Virology T32 training grant. We take a multidisciplinary approach to study the tumor microenvironment of human papilloma virus (HPV)-associated head and neck cancer. The fellow will conduct independent and collaborative translational research using mouse and human models and resulting in presentations and publications. The techniques involved will include working with mouse models of head and neck cancer and carefully studying the tumor microenvironment using flow cytometry, multiplexed-immunohistochemistry, gene expression analyses (qPCR), protein assessment (ELISA) and others. Manipulation of these model systems with cell cycle checkpoint-targeting as well as immune-based therapies are commonplace in the lab. These in vivo studies will be supplemented by ex vivo studies using organotypic tumor slice cultures of human HPV+ head and neck tumors. The ability to analyze the complex datasets resulting from the above experimentation is essential.

Application Deadline: Open Until Filled

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